人眼视神经组织形态学研究视神经纤维计数和直径及视盘面积的测定

目的通过测量正常人眼视神经纤维数量、直径及视盘面积，为青光眼视神经损害研究奠定基础，并对其相互关系进行分析。方法应用一种计算机图像分析系统对15只正常人眼视神经断面和视盘进行检测。结果平均视神经纤维数为（10.08±1.61）×10⁵，神经纤维平均直径为（0.99±0.04）μm，平均视盘面积为（2.28±0.61）mm²。视神经纤维数随神经断面面积的增加而增加，而与视盘面积无关。结论本研究为临床推测视神经损害的预后及进一步研究青光眼的神经损害奠定了一定的基础。(中华眼底病杂志,1999,15:16-19)

The histomorphology study of human optic nerves: Measurement of optic nerve fiber number and diameterand optic disc area

ObjectiveTo lay a foundation for study of optic narve damage in glaucoma by measuring the number and diameter of the optic nerve fibers and optic disc area in normal individuals. MethodsThe cross-sections of the optic nerve and the optic discs in 15 normal human eyes were examined with the use of a computerized image analysis system. ResultsThe mean nerve fiber count was 10.08×10⁵±1.61×10⁵. The mean nerve fiber diameter was (0.99±0.04)μm. The nerve fiber count increased significantly with the increasing of cross-section area of the optic nerve, but the nerve fiber count was independent of the optic dise area. ConclusionThis study provided anatomic basis for predicting the prognosis of optic nerve damage and further studyv of nerve damage in glaucoma. (Chin J Ocul Fundus Dis,1999,15:16-19)