经鼻导管高流量吸氧与经鼻气道正压通气在重症毛细支气管炎呼吸支持中的应用价值比较

目的:比较经鼻导管高流量吸氧(HFNC)与经鼻气道正压通气(nCPAP)在重症毛细支气管炎呼吸支持中的应用价值,为临床治疗方案的选择提供参考.方法:选取2016年12月至2018年12月我院儿科收治的重症毛细支气管炎患儿90例,采用随机数表法分为观察组和对照组各45例.两组患儿入院后均给予常规综合治疗以保证呼吸道通畅,...

Comparison of Application Value of High Flow Nasal Cannula and Nasal Continuous Positive Airway Pressure in Respiratory Support for Severe Bronchiolitis

Objective: To compare the application value of high flow nasal cannula (HFNC) and nasal continuous positive airway pressure (nCPAP) in respiratory support for severe bronchiolitis, so as to provide reference for the selection of clinical treatment regimen. Methods: A total of 90 children with severe bronchiolitis admitted into the pediatrics of our hospital from Dec. 2016 to Dec. 2018 were enrolled to be divided into the observation group and the control group via the random number table, with 45 cases in each group. After admission, two groups were given conventional comprehensive treatment to ensure the smoothness of respiratory tract. On this basis, the observation group was treated with HFNC, and the control group was given nCPAP. The respiratory rate, transcutaneous oxygen saturation (TcSO2), respiratory distress clinical score system (CSS) score, arterial partial pressure of oxygen (PaO2) and other respiratory related indicators before treatment and after treatment of 24 h and improvement of clinical symptoms and signs before and after treatment were compared between two groups. Results: The respiratory rate and CSS score of two groups significantly decreased after treatment of 24 h, and the degree of reduction was more obvious in the observation group. TcSO2 and PaO2 of two groups significantly increased after treatment of 24 h, and the ascending range in the observation group was significantly larger than that in the control group. After treatment, clinical symptoms of cough, lung rales and lung inflammation were improved in both groups. The disappearance time of symptoms and signs in the observation group was significantly shorter than that in the control group, with statistically significant differences (P<0.05). Conclusion: HFNC in respiratory support for children with severe bronchiolitis can significantly improve the ventilation function and clinical symptoms. The therapeutic effects of HFNC are better than that of nCPAP, and the sample size could be enlarged for further observation.