中药沐足联合穴位贴敷改善AECOPD痰热壅肺证患者呼吸道症状的临床研究

目的探讨中药沐足联合穴位贴敷改善慢性阻塞性肺疾病急性加重(acute exacerbation of chronic obstructive pulmonary disease,AECOPD)痰热壅肺证患者呼吸道症状的临床效果。方法选择2017年1月～2018年5月在我院诊断治疗的AECOPD痰热壅肺证患者100例为研究对象,随机分为治疗组与对照组,各50例。对照组采用常规治疗与护理,治疗组在对照组基础上给予中药沐足与穴位贴敷。观察两组患者临床疗效,比较两组患者治疗前后咳嗽、咳痰、气喘症状积分、氧分压(PaO2)、二氧化碳分压(PaCO2)、血氧饱和度(SaO2)水平及C反应蛋白(C-reactive protein,CRP)水平。结果与治疗前比较,治疗后两组患者咳嗽、咳痰、气喘积分均呈下降趋势,差异有统计学意义(P0.05);治疗后,治疗组咳嗽、咳痰、气喘积分显著低于对照组,差异有统计学意义(P0.05)。与治疗前比较,治疗后两组患者PaO2、SaO2水平呈上升趋势,PaCO2水平呈下降趋势,差异有统计学意义(P0.05);且治疗后,治疗组PaO2、SaO2水平显著高于对照组,PaCO2水平显著低于对照组,差异有统计学意义(P0.05)。与治疗前比较,治疗后两组患者CRP水平均呈下降趋势(P0.05);且治疗后,治疗组CRP水平显著低于对照组,差异有统计学意义(P0.05)。秩和检验显示,治疗组的临床疗效优于对照组,治疗组临床控制率(70.0%)显著高于对照组(20.0%),差异有统计学意义(P0.05)。结论中药沐足联合穴位贴敷可显著改善AECOPD痰热壅肺证患者的临床症状、肺功能,降低炎性指标,提高临床疗效。

Clinical study on the improvement of respiratory tract symptoms in AECOPD patients with phlegm-heat obstructing lung syndrome by herbal foot massage combined with acupoint application

Objective To explore the clinical study on the improvement of respiratory tract symptoms in AECOPD patients with phlegm-heat obstructing lung syndrome by herbal foot massagecombined with acupoint application.Methods From January 2017 to May 2018,100 AECOPD patients with phlegm-heat obstruction of the lung syndrome diagnosed and treated in our hospital were selected as the research objects.They were randomly divided into treatment group and control group,50 cases in each group.The control group was treated with routine treatment and nursing,while the treatment group was treated with herbal foot massage and acupoint application of traditional Chinese medicine on the basis of the control group.The clinical effect on the patients were observed in the two groups,symptom score of cough,sputum,wheezing,PaO2,PaCO2,SaO2and CRP levels before and after treatment were compared between the two groups.Results After treatment,the scores of cough,expectoration and asthma in both groups showed a downward trend compared with those before treatment,there was a significant difference(P<0.05).After treatment,the scores of cough,sputum and asthma in the treatment group were significantly lower than those in the control group(P<0.05).After treatment,the levels of PaO2and SaO2in the two groups showed an upward trend,while the level of PaCO2showed a downward trend,there was a significant difference between the two groups before treatment(P<0.05).After treatment,PaO2and SaO2in the treatment group were significantly higher than those in the control group,and PaCO2was significantly lower than those in the control group(P<0.05).After treatment,the levels of CRP in both groups showed a downward trend compared with before treatment,and there was a significant difference(P<0.05).After treatment,the CRP level in the treatment group was significantly lower than that in the control group(P<0.05).Rank sum test showed that the clinical efficacy of the treatment group was better than that of the control group,the clinical control rate (70.0%)was significantly higher than that in the control group (20.0%),the difference was statistically significant(P<0.05).ConclusionHerbal foot massagecombined with acupoint application can significantly improve the clinical symptoms and lung function of AECOPD patients with phlegm-heat obstruction of lung syndrome,reduce inflammatory indicators and improve clinical efficacy.