| 缩宫素及其类似物的研究进展 |
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| 引用本文： | 刘倩,钱德明,刘群丽,高华. 缩宫素及其类似物的研究进展[J]. 药物分析杂志, 2011, 0(3) |
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| 作者姓名： | 刘倩 钱德明 刘群丽 高华 |
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| 作者单位： | 中国药品生物制品检定所; |
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| 摘 要： | 缩宫素作为催产、引产的首选药物已经在临床上应用多年。本文简述了缩宫素及缩宫素受体的结构、分布及生理功能,介绍了对缩宫素结构修饰而产生的一系列类似物及其不同的生物活性,并对该类化合物在临床上的应用情况和前景进行了介绍和总结。
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| 关 键 词： | 缩宫素 缩宫素类似物 临床应用 |
Research progress of oxytocin and its analogues |
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| LIU Qian,QIAN De-ming,LIU Qun-li,GAO Hua. Research progress of oxytocin and its analogues[J]. Chinese Journal of Pharmaceutical Analysis, 2011, 0(3) |
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| Authors: | LIU Qian QIAN De-ming LIU Qun-li GAO Hua |
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| Affiliation: | LIU Qian,QIAN De-ming,LIU Qun-li,GAO Hua*(National Institute for Pharmaceutical and Biological Products,Beijing 100050,China) |
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| Abstract: | Oxytocin as a preferred medication for labour induction has been used in clinical for many years.This article outlines the structure,distribution and physiological function of oxytocin and oxytocin receptor.A series of oxytocin analogues modified in different positions of oxytocin structure and different biological activity of these analogues are described.The application and prospects at of these compounds in clinical practice are also summarized. |
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| Keywords: | oxytocin oxytocin analogues clinical application |
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