| 毛细管气相色谱法同时测定少林风湿跌打膏中薄荷脑、水杨酸甲酯和冰片的含量 |
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| 引用本文： | 傅应华.毛细管气相色谱法同时测定少林风湿跌打膏中薄荷脑、水杨酸甲酯和冰片的含量[J].药物分析杂志,2011(6). |
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| 作者姓名： | 傅应华 |
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| 作者单位： | 嘉兴学院医学院; |
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| 摘 要： | 目的:建立毛细管气相色谱法同时测定少林风湿跌打膏中薄荷脑、水杨酸甲酯和冰片的含量。方法:采用水蒸气蒸馏法提取制备样品溶液。HP-INNOWax Polyethylene Glycol(30 m×0.35 mm×0.25μm)石英毛细管色谱柱,柱温110℃,进样口温度200℃,氢火焰离子化检测器(FID),分流进样,分流比10.0∶1,载气为氮气,流速1.0 mL.min-1,进样量1μL。结果:薄荷脑在0.423~2.642 mg.mL-1范围内与峰面积呈良好线性关系(r=0.9999),水杨酸甲酯在0.405~2.532 mg.mL-1范围内与峰面积呈良好线性关系(r=0.9999),冰片在0.412~2.575 mg.mL-1范围内与峰面积呈良好线性关系(r=0.9999);平均加样回收率薄荷脑为102.2%(RSD=2.0%),水杨酸甲酯为102.1%(RSD=2.0%),冰片为102.5%,(RSD=2.0%)。结论:本方法简便、准确、重现性好,可用于少林风湿跌打膏制剂及中间体的质量控制。
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| 关 键 词： | 气相色谱法 薄荷脑 水杨酸甲酯 冰片 中成药 测定 蒸馏 提取 |
Capillary gas chromatography simultaneous determination of menthol,methyl salicylate and synthetic borneol in Shaolin Fengshi Dieda extract |
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| FU Ying-hua.Capillary gas chromatography simultaneous determination of menthol,methyl salicylate and synthetic borneol in Shaolin Fengshi Dieda extract[J].Chinese Journal of Pharmaceutical Analysis,2011(6). |
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| Authors: | FU Ying-hua |
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| Institution: | FU Ying-hua (Medical College of Jiaxing University,Jiaxing 314001,China) |
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| Abstract: | |
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| Keywords: | gas chromatography menthol methyl salicylate synthetic borneol Chinese patent drug assay distillation extract |
| 本文献已被 CNKI 等数据库收录！ |
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