3.0 T MR T2 mapping对膝关节软骨损伤的研究

目的评价3.0 T MR T2 mapping成像技术对膝关节早期软骨病损评价的临床应用价值。材料与方法采用3.0 T高场强MR成像仪分别对膝关节病变组(A组)和健康对照组(B组)各100例进行MR T2 mapping成像,将膝关节软骨分为11个区(股骨内侧中区、内侧后区、外侧中区和外侧后区,胫骨内侧前区、内侧中区、内侧后区、外侧前区、外侧中区和外侧后区、髌骨软骨面区),测量其T2值,并进行统计学分析。结果 A组关节软骨T2平均值为(44.39±15.28) ms,B组关节软骨T2平均值为(31.70±8.33) ms,A组关节软骨T2值高于B组,两组间差异具有统计学意义(P<0.05)。A组T2值与WORMS评分具有的相关性(r=0.405～0.847,P<0.01)。结论 MR T2 mapping成像可以有效反应早期关节软骨损伤T2值的变化,是评价膝关节软骨病损的有效手段。

T2 mapping of knee cartilage damage at 3.0 T MR imaging

Objective： To evaluate early knee cartilage damage with T2 mapping at 3.0 T MRl. Materials and methods： T2 mapping of knee cartilage was evaluated quantitatively at a 3.0 T MRI scanner in 100 patients with osteoarthritis, rheumatoid arthritis, cartilage injury respectively and in 100 healthy subjects （group B）. T2 value in eleven compartments of knee cartilage （central medial femoral region, posterior medial femoral region, central lateral femoral region, posterior lateral femoral region, anterior medial tibial region, central medial tibial region, posterior medial tibial region, anterior lateral tibial region, central lateral tibial region, posterior lateral tibial region, patella region） were measured respectively in T2 mapping imaging. Statistical differences and the correlation between T2 value and WORMS scores were analyzed. Results： The everage T2 relaxation time for knee cartilage damaged group （group A） and healthy subjects （group B） were （44.39 ± 15.28） ms and （31.70 ± 8.33） ms respectively. T2 values of the former group were significantly higher than those in later group. Significant difference was found between these two groups （P〈0.05）. T2 values of knee cartilage damaged group were highly correlated with WORMS scores （r=0.405--0.847, P〈0.01）. Conclusion： T2 mapping imaging can demonstrate early knee articular cartilage damage, and it is of a high clinical value modality for articular cartilage evaluation.