MERKEL CELL TUMOR COEXPRESSING CYTOKERATIN AND NEUROFILAMENT PROTEINS |
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Authors: | Yoshito Sadahira Shu Nakamoto Masaharu Mori Chao Liang Hsueh Michiyasu Awai |
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Affiliation: | Department of Pathology, Okayama University Medical School, Okayama |
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Abstract: | Whorled filaments 10 nm in width were identified by anti-intermediate filaments antibodies in a Merkel cell tumor from a 52-year-old man. Immunohistochemlcal tests revealed that the tumor was stained with anti-keratin antibody and antibodies against the 68-kd and 200-kd subunits of neurofilament proteins but not antibody against the 150-kd subunlt. This is the first reported case of Merkel cell tumor expressing a 200-kd subunit of neurofilament proteins. |
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