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阻断围产期乙型肝炎垂直传播——妊娠后期乙肝疫苗接种
引用本文:胡桂英,马金赏,谭文华,刘应林,康志海,张景权.阻断围产期乙型肝炎垂直传播——妊娠后期乙肝疫苗接种[J].现代妇产科进展,1991(Z1).
作者姓名:胡桂英  马金赏  谭文华  刘应林  康志海  张景权
作者单位:哈尔滨医科大学附属二院妇产科,哈尔滨医科大学附属二院妇产科,哈尔滨医科大学附属二院妇产科,哈尔滨医科大学附属二院传染科,哈尔滨医科大学附属二院妇产科,哈尔滨医科大学附属二院妇产科 指导,指导,指导
摘    要:29例20—30岁的妊娠妇女(血中无HBV标志物),于妊娠后期接种乙肝疫苗,观察乙肝疫苗的免疫原性、安全性及胎儿抗体转运情况。追综观察新生儿出生后乙肝表面抗体阳转率。共观察29例,生后一个月抗—HBs阳转率89.6%,生后三个月抗—HBs阳转率86.3%,生后六个月抗—HBs阳转率75.8%,说明妊娠后期接种乙肝疫苗有较强的免疫原性,这种免疫作用可持续到孩子较大适于预接种的时候。

关 键 词:围产期  阻断HBV(乙肝病毒)  垂直传播  乙肝疫苗

The Block of Perinatal HBV Vertical Transmission——HBV Vaccine Immunization duriug Late Pregnaney
Abstract:Twenty-nine pregrant women (no HBV marks in blood) with 20-30 years old were immuned by HBV vaccine during late pregnantperiod. The immuno-antigenicity、security and fetal antibody transferrencewere observed. The positive transferrent rate of Anti-HBV of thenewborns was also observed. The Anti-HBV positive transferent ratefwas 89.6% during one month after delivery, 86.3% during three monthsfter delivery and 75.8% during six months. The data indcates that thepregnant women immuned by HBV vaccine during late pregnant periodhave strong immunoantigenicity, and the immunising action can persistaor a long time until the child will be suitable for preventiveinoculation.
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