16层螺旋CT冠状动脉成像在冠心病诊断中的应用研究

目的评价16层螺旋CT冠状动脉成像的临床应用价值,探讨提高冠状动脉成像质量的方法。方法40例患者行16层螺旋CT冠状动脉成像,选取图像质量较佳的22例患者,进行选择性冠状动脉造影检查,将两者结果对照分析。结果88支冠状动脉,多层螺旋CT冠状动脉成像(MSCTCA)诊断冠状动脉狭窄的敏感性为86.80%,特异性为86.20%,阳性预测率为76.47%,阴性预测率92.59%,假阳性率13.70%,假阴性率13.30%。对诊断有临床意义的冠状动脉狭窄的敏感性为90.0%,特异性为70.0%,阳性预测率为60.0%,阴性预测率93.3%,假阳性率30.0%,假阴性率10.0%。两者对冠状动脉狭窄诊断差异无统计学意义。结论16层螺旋CT冠状动脉成像技术是一项可靠的冠心病诊断方法,作为一项非创伤性技术,是评价冠状动脉狭窄病变的重要筛选手段。

The clinical application of sixteen-slice spiral CT angiography of coronary artery in the diagnosis of coronary heart disease

Objective To evaluate the value of sixteen-slice spiral CT angiography of coronary artery in the diagnosis of coronary heart disease. Methods Sixteen-slice spiral CT angiography was performed in 40 patients.The patency of coronary artery and other branches was examined, the distribution and extent of coronary stenosis were assessed. The findings demonstrated on sixteen-slice spiral CT angiography were compared with those seen on selective coronary angiography. Results Among the 88 coronary arteries, in the evaluation of the coronary arteries by sixteen-slice spiral CT angiography, the sensitivity of the detection of coronary artery was 86.80%,the specificity was 86.20%,the positive predictive and negative predictive value was 76.47%,92.59%,respectively. The evaluation of the significant coronary arteries stenosis, the sensitivity, specificity ,the positive predictive value and negative predictive value was 90.0%,70.0%,60.0%,93.3%,respectively. Conclusion Sixteen-slice spiral CT angiography is a reliable diagnostic method of coronary heart disease .It is valuable in demonstrating coronary lumen stenosis. It should be used as a reliable exam of coronary heart disease in clinical practice.