| 消瘀化痰饮对非酒精性脂肪肝大鼠脂质代谢和肝组织形态学的影响 |
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| 引用本文： | 苗卉,魏翠萍,魏春娥,张一昕.消瘀化痰饮对非酒精性脂肪肝大鼠脂质代谢和肝组织形态学的影响[J].河北中医药学报,2007,22(2):3-5. |
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| 作者姓名： | 苗卉 魏翠萍 魏春娥 张一昕 |
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| 作者单位： | 河北医科大学中医学院,石家庄,050091 |
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| 基金项目： | 河北省教育厅博士基金课题(B2004411) |
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| 摘 要： | 目的:观察中药消瘀化痰饮对NAFLD大鼠脂质代谢和肝组织形态学的影响。方法:采用喂饲高脂饲料的方法复制NAFLD大鼠模型,以东宝肝泰为对照药,检测各组大鼠血清TC、TG、FFA、ALT、AST和肝组织中TC、TG的含量或活性改变,并观察了肝组织形态学的变化。结果:消瘀化痰饮能明显降低模型大鼠血清和肝脏组织中TC、TG、FFA的含量,降低血清ALT、AST的活性,改善肝组织的病变程度。结论:消瘀化痰饮能够促进脂质代谢、保护肝功能,呈现出良好的防治NAFLD的作用。
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| 关 键 词： | 消瘀化痰饮 非酒精性脂肪肝 脂质代谢 形态学 |
| 文章编号： | 1007-5615（2007）02-0003-03 |
| 收稿时间： | 2007-04-08 |
| 修稿时间： | 2007年4月8日 |
Effect of Xiaoyu Huatan Yin on Lipid Metabolism of Rats with Non-alcoholic |
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| MIAO Hui WEI Cui-ping WEI Chun-e et al TCM College Hebei Medical University.Effect of Xiaoyu Huatan Yin on Lipid Metabolism of Rats with Non-alcoholic[J].Journal of Hebei Traditional Chinese Medicine and Pharmacology,2007,22(2):3-5. |
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| Authors: | MIAO Hui WEI Cui-ping WEI Chun-e TCM College Hebei Medical University |
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| Institution: | shijiazhuang 050091 |
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| Abstract: | Objective:to observe the Effect of Xiaoyu Huatan Yin on lipid metabolism of NAFLD rats. Methods: NAFLD rats were prepared by feeding high fat forage. With thecomparison to Dongbao Gantai, TC, TG, FFA, ALT, AST in blood serum and TC and TG contents or activeness were examined and morphologicchanges in hepatic tissues. Results: Xiaoyu Huatan Yincould significantly decrease TC, TG and FFA in blood serum and hepatic tissues of NAFLD rat model, reduce ALT and AST activeness, improve the pathological changes. Conclusion:Xiaoyu Huatan Yincan promote lipid metabolism, protect liver function, prevent and cure NAFLD. |
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| Keywords: | Xiaoyu Huatan Yin Non-alcoholic Fatty Liver lipid metabolism morphology |
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