阻塞性睡眠呼吸暂停低通气综合征与临床相关因素的评估

目的探讨年龄、肥胖、颈围等与阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的发病和严重程度的相关关系。方法选取111例怀疑为OSAHS的病例,全部病例均进行至少1次的夜间多导睡眠仪检测并记录身高、体质量、颈围,并计算体质量指数(BMI)。分析年龄、颈围、BMI、最低SaO2、呼吸紊乱指数(RDI)之间的相关关系。结果颈围、Epworth评分、BMI、最低氧饱和度(SaO2)与RDI在统计学上有非常显著的相关关系。同时,以上因素与OSAHS的严重程度亦有明显的相关关系(P<0.05)。但RDI与年龄并无相关关系。分别以颈围42 cm,或以BMI 28为界进行分组比较,2组间RDI的比较差异均有统计学意义(P<0.05)。并将以上因素进行回归分析推导出线性回归方程。结论由于颈围、BMI、ESS评分和最低SaO2与RDI良好的相关性,临床上可作为OSAHS患者的简便、可靠的监测指标。

Evaluation of Clinical Parameters in Patients with Obstructive Sleep Apnea Hypopnea Syndrome

Objective This article focuses on the possible correlation of the clinical parameters(such as age,gender,neckcircumference) with the severity of Obstructive sleep apnea /hypopnea syndrome(OSAHS).Methods 111 patients presenting withclinical symptoms of OSAHS were asked to attend the study.All patients underwent at least a polysomnography and the physical examination,which included neck circumference,and body mass index(BMI).The correlation between age,neck circumference,BMI,SaO₂ and respiratory disturbance index(RDI) were analyzed.Results A statistically significant correlation between neck circumference,the lowest SaO₂,the Epworth sleepiness scales and BMI with the RDI was detected.The difference of neck circumference,ESS,SaO₂,and the BMI was significant between the different serious patients.No correlation was found between age and RDI.Our data suggests that when BMI≥28,or neck circumference≥42 cm,the possibility of OSAHS is high.Conclusion BMI,ESS,SaO₂ and neck circumference are rapid,simple and reliable method on assessing the serous of OSAHS.