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γ线立体定向放射治疗脑转移瘤的疗效
引用本文:魏瑞,马志明,等.γ线立体定向放射治疗脑转移瘤的疗效[J].湖南医科大学学报,2001,26(5):451-452.
作者姓名:魏瑞  马志明
作者单位:[1]中南大学附属湘雅医院放疗科,长沙410008 [2]中南大学附属湘雅医院神经外科,长沙410008
摘    要:目的:比较γ线立体定向放射治疗(SRT)加全脑放疗与常规放疗脑转移瘤的疗效。方法:采用SRT+全脑放疗脑转移瘤43例,常规放疗脑转移瘤50例。SRT周边剂量15-27Gy,全脑放疗30-40Gy。结果:SRT+全脑放疗组病人1年生存率和中位生存时间及肿瘤局控率均较常规放疗组增高或延长(P<0.01)。死亡原因中,SRT+全脑放疗组死于脑转移者较常规放疗组低(P<0.05),结论:SRT+全脑放疗治疗脑转移瘤的疗效优于常规放疗。

关 键 词:γ射线  脑肿瘤  立体定向放射治疗  脑转移瘤

Therapeutic effect of gamma-ray stereotactic radiotherapy on brain metastases]
R Wei,Z M Ma,J Yuan.Therapeutic effect of gamma-ray stereotactic radiotherapy on brain metastases][J].Bulletin of Hunan Medical University,2001,26(5):451-452.
Authors:R Wei  Z M Ma  J Yuan
Institution:Department of Radiation Oncology, Xiangya Hospital, Central South University, Changsha 410008, China.
Abstract:OBJECTIVE: To evaluate the therapeutic effects of gamma-ray stereotactic radiotherapy (SRT) plus whole brain irradiation and radiotherapy alone in brain metastases. METHODS: Forty-three patients with brain metastases were treated by SRT plus whole brain irradiation and 50 patients were treated by routine radiotherapy. SRT was given with the dosage of 15-27 Gy, and whole brain irradiation was given with the dosage of 30-40 Gy. RESULTS: One-year survival rate, median survival period, and tumor local control rate in SRT plus whole brain irradiation group were higher or longer than those in the routine radiotherapy group (P < 0.01). Mortality in SRT plus whole brain irradiation group was lower than that in the routine radiotherapy group (P < 0.05). CONCLUSION: The therapeutic effect of SRT plus whole brain irradiation on brain metastasis of cancer is superior to the routine radiotherapy.
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