| 颈痛灵乳膏提取工艺研究 |
| |
| 引用本文： | 张锦聪,王立兴.颈痛灵乳膏提取工艺研究[J].海峡药学,2014(3):22-24. |
| |
| 作者姓名： | 张锦聪 王立兴 |
| |
| 作者单位： | 福州长富星生物医药科技有限公司,福州350002 |
| |
| 摘 要： | 目的：优选颈痛灵乳膏的最佳提取工艺。方法采用高效液相色谱法.以红花中羟基红花黄色素 A为指标.正交试验设计考察乙醇浓度、溶媒用量、提取时间、提取次数对提取效果的影响。结果颈痛灵乳膏的提取工艺确定为A2 B2 C3 D2，即加入10倍量70％乙醇回流提取2次，每次提取时间为1.5h。结论此工艺对羟基红花黄色素A的提取率高，稳定性好，适合工业化生产。
|
| 关 键 词： | 颈痛灵乳膏 羟基红花黄色素A 高效液相色谱法 正交试验 提取工艺 |
Studies on the extraction techonology of Jingtong Ling Cream |
| |
| ZHANG Jin-cong,WANG Li-xing.Studies on the extraction techonology of Jingtong Ling Cream[J].Strait Pharmaceutical Journal,2014(3):22-24. |
| |
| Authors: | ZHANG Jin-cong WANG Li-xing |
| |
| Institution: | ( Fuzhou Changfuxing Biopharmaceutical Science and Technology Co. Ltd Fuzhou 350002, China) |
| |
| Abstract: | OBJECTIVE To optimize the extraction techonology of Jingtongling Cream.METHODS With the content of hydroxysafflor yellow A in Carthamus Tinctorius L as index ,the optimum extraction condition for the etha-nol concentration,volume,extractoin time and times were selected by orthogonal design.The content of Safflor Yellow A were determind by HPLC.RESULTS The certain extraction techonology of Jingtong Ling Cream was A 2 B3 C3 D2 , The addition of 10 times of 70% ethanol was added and extracted 3 times.Extraction time was 1.5 hours.CONCLUSION This process has high rate for the hydroxysafflor yellow A extraction ,good stability ,suitable＆amp;nbsp;for industrial production. |
| |
| Keywords: | Jingtongling Cream Hydroxysafflor yellow A HPLC Orthogonal test Extraction techonology |
| 本文献已被 CNKI 维普 等数据库收录！ |
