| Abstract: | SummaryA double-blind crossover clinical trial is reported on the effects of naproxen in two doses, 500?mg. and 750?mg. daily, and 100?mg. indomethacin daily in 23 patients with classical rheumatoid arthritis, each drug being given for 1 week. The results show that there was little to choose between the drugs and that there was clinical equivalence between the two doses of naproxen. Radioactive pertechnetate (99mTc) joint uptakes were depressed by both naproxen and indomethacin, indicating anti-inflammatory effect. |
