Effect of X-ray radiation exposure on lyophilized recombinant activated factor VII (formulated for storage at room temperature)

Abstract

Objective:

To investigate effects of air transport and X-ray radiation exposure through airport security of a new room temperature-stable rFVIIa formulation (NovoSeven/NovoSeven RT, Novo Nordisk A/S, Bagsværd, Denmark) lyophilized using in vitro study methodology, thus evaluating possible effects of exposure through airport security and airplane travel.