| 人类白细胞抗原-G及其与妇科肿瘤的关系 |
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| 引用本文： | 韩雪川,赵兴波. 人类白细胞抗原-G及其与妇科肿瘤的关系[J]. 国际肿瘤学杂志, 2009, 36(2). DOI: 10.3760/cma.j.issn.1673-422X.2009.02.022 |
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| 作者姓名： | 韩雪川 赵兴波 |
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| 作者单位： | 山东大学附属省立医院妇产科,济南,250021;山东大学附属省立医院妇产科,济南,250021 |
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| 摘 要： | 免疫逃逸在妇科恶性肿瘤发病中的作用日益受到重视.人类白细胞抗原-G(HLA-G)分子是主要组织相容复合物Ⅰ家族中的主要成员,具有抑制免疫的作用,在妇科肿瘤的免疫逃逸中发挥了重要作用.
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| 关 键 词： | HLA抗原 组织相容性抗原Ⅰ类 免疫耐受 生殖器肿瘤 女(雌)性 |
Correlation between human leukocyte antigen G and gynecological neoplasms |
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| HAN Xue-chuan,ZHAO Xin-bo. Correlation between human leukocyte antigen G and gynecological neoplasms[J]. Journal of International Oncology, 2009, 36(2). DOI: 10.3760/cma.j.issn.1673-422X.2009.02.022 |
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| Authors: | HAN Xue-chuan ZHAO Xin-bo |
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| Abstract: | The immune tolerance or immune escape plays important roles in the genesis and progression of malignant gynecological neoplasms.Human leukocyte antigen G(HLA-G)is an important member of major histocompatiblity complex class Ⅰ.HLA-G seems to affect almost every aspect of human immunity.It can inhibit immunological function,and play an important role in immune escape of malignant gynecological neoplasms. |
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| Keywords: | HLA antigens Histocompatibility antigens class Ⅰ Immune tolerance Genital neoplasm,female |
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