射频消融治疗腹膜后和盆腔恶性肿瘤

目的]探讨射频消融治疗腹膜后和盆腔恶性肿瘤的疗效和安全性.方法]腹膜后和盆腔恶性肿瘤患者9例,均为单发病灶.其中原发性肾上腺梭形细胞瘤术后复发1例,软骨肉瘤术后腹膜后转移2例,肺癌、恶性胸腺瘤术后1例,胰腺癌腹膜后转移1例,直肠癌和子宫颈癌术后盆腔转移各1例.CT引导下进行射频消融术.结果]腹膜后和盆腔肿块射频消融术共19次,平均2.1次.9例患者临床症状不同程度减轻或消失,临床缓解率100%.增强CT复查完全热凝固坏死4例,不完全坏死3例,部分坏死2例.患者术中较好地耐受治疗,术后未发生严重并发症.结论]射频消融治疗腹膜后和盆腔恶性肿瘤安全,对直径小于6cm的肿瘤疗效确切.

Radiofrequency Ablation for Retroperitoneal and Pelvic Malignancies

Purpose] To evaluate the efficacy and safety of CT guided radiofrequency ablation (RFA) for treatment of unresectable or recurrent retroperitoneal and pelvic malignancy. Methods] RFA was performed on 9 patients with unresectable or recurrent retroperitoneal or pelvic malignancies from adrenal (n=1), chondrosarcomas (n=2), lung carcinoma (n=1), thymus malignant tumor (n=1), pancreatic carcinoma (n=1), rectal carcinoma (n=1) and cervix carcinoma (n=1). Under CT guidance, 9 patients were performed RFA by percutaneous approach. Results] RFA was performed 19 times (mean, 2.1). Symptoms in all 9 cases were relieved in certain degree after RFA procedure. The complete hyperthermic coagulation, incomplete hyperthermic coagulation, and partial hyperthermic coagulation occurred in 4, 3, 2 cases, respectively. RFA was successfully completed in all operations without intraoperative complications. There was no severe postoperative complication. Conclusions] Under CT guidance, RFA treatment for unresectable or recurrent retroperitoneal or pelvic malignancies from different origins is safe, and treatment for tumor less than 6cm diameter can make complete coagulation.