| 1，6－二磷酸果糖治疗重型脑梗死 |
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| 引用本文： | 杨霞峰,张洪军,秦绍林,赵彩君,肖太荣.1，6－二磷酸果糖治疗重型脑梗死[J].中国新药与临床杂志,1996(2). |
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| 作者姓名： | 杨霞峰 张洪军 秦绍林 赵彩君 肖太荣 |
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| 作者单位： | 聊城地区东昌医院 |
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| 摘 要： | 目的：观察１，６－二磷酸果糖（ＦＤＰ）治疗重型脑梗死的疗效。方法：重型脑梗死３２例（男性２１例，女性１１例，年龄５９±ｓ１２３），在常规药物治疗的同时加用１，６－二磷酸果糖５ｇ，溶于注射用水５０ｍＬ中静脉滴注，ｂｉｄ～ｑｉｄ，连用５～７ｄ；并与对照组３２例（男性１８例，女性１４例，年龄５８±１１ａ）进行比较。结果：对照组和ＦＤＰ组的显效率分别是５６％和８１％，总有效率分别是７２％和９４％。结论：ＦＤＰ组疗效明显优于对照组（Ｐ＜０．０５），无毒副作用，说明该药对脑梗死急性期有应用价值。
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| 关 键 词： | 己糖二磷酸盐类 脑梗死 缺氧症 1，6－二磷酸果糖 |
Treatment of severe cerebral infarction with fructose 1,6-diphosphate |
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| YANG Xia-Feng, ZHANG Hong-Jun, QIN Shao-Lin, ZHAO Cai-Jun, XIAO Tai-Rong.Treatment of severe cerebral infarction with fructose 1,6-diphosphate[J].Chinese Journal of New Drugs and Clinical Remedies,1996(2). |
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| Authors: | YANG Xia-Feng ZHANG Hong-Jun QIN Shao-Lin ZHAO Cai-Jun XIAO Tai-Rong |
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| Abstract: | AIM: To observe the efficacy of fructose 1, 6-diphosphate (FDP) in the treatment of severe cerebral infarction. METHODS: Thirty-two patients with severe cerebral infarction (M 21, F 11, age 59±s 12 a) were given FDP 5 g in distilled water 50 mL iv, gtt, bid-qid for 5-7 d in addition to conventional therapy. The other similar thirty-two patients (M 18, F14,age 58±11 a) received conventional therapy (20% mannitol 250 mL iv,q6-8h for 10-15d, citicoline, piracetam). RESULTS: Results showed that the total response rate was 94% in the former group and 72% in the latter group (P<0.05) . CONCLUSION: We think that FDP may be a valuable drug in treating acute cerebral infarction. |
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| Keywords: | hexosedihosphates cerebral infaraction anoxia fructose 1 6-diphosphate |
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