Changes in the peripheral blood and bone marrow of rabbits in experimental epilepsy

Summary The effect of experimentally induced cardiazol epilepsy on the peripheral blood and bone marrow was studied in 16 rabbits. The epileptiform attacks provoked leukocytosis and a rise of the red cell count. The leukocytic reaction appeared during the first few minutes of an increased number of lymphocytes, and later on of pseudoeosinophils. Following several attacks, an intensified granulopoiesis and an increased number of platelet producing forms of megakaryocytes were observed in the bone marrow.There were no modifications in the red blood picture.The author concludes that the changes occuring in the blood are connected with the intensified bone marrow function, under the effect of epilepitform fits.(Presented by Active Member AMN SSSR V. V. Parin) Translated from Byulleten' éksperimental'noi biologii i meditsiny Vol. 49, No. 2, pp. 61–64, February, 1960.