| 抗结核药物所致肝损害129例临床分析 |
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| 引用本文： | 薛卉,邢丽华,崔建立,张彩莲,秦超,杜钟珍.抗结核药物所致肝损害129例临床分析[J].中国城乡企业卫生,2014(6):89-90. |
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| 作者姓名： | 薛卉 邢丽华 崔建立 张彩莲 秦超 杜钟珍 |
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| 作者单位： | 天津市海河医院结核科,天津300350 |
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| 摘 要： | 目的探讨抗结核药致药物性肝损害（DILI）的临床特点。方法回顾分析我科129例肺结核患者在抗结核治疗过程中发生DILI的临床资料。结果高龄、嗜酒、肝炎病毒携带者或有肝病史、抗结核药物治疗的1~3周、血行播散型肺结核更易发生药物性肝损害。结论对抗结核药致DILI的早期诊断和及时合理治疗,以保证患者能够顺利完成化疗。
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| 关 键 词： | 抗结核药物 肝损害 临床分析 |
Clinical analysis of 129 cases of liver damage caused by anti-tuberculosis drugs |
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| XUE Hui,XING Li-hua,CUI Jian-li,ZHANG Cai-lian,QIN Chao,DU Zhong-zhen.Clinical analysis of 129 cases of liver damage caused by anti-tuberculosis drugs[J].Chinese Journal Urban and Rural Industrial Hygiene,2014(6):89-90. |
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| Authors: | XUE Hui XING Li-hua CUI Jian-li ZHANG Cai-lian QIN Chao DU Zhong-zhen |
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| Institution: | (Tianjin Haihc Hospital Department of tuberculosis, Tianjin 300350, China) |
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| Abstract: | Objective to investigate the drug-induced liver damage caused by anti- tuberculosis drugs （DILI） clinical characteristics. Methods Retrospective analysis clinical data of 129 cases of pulmonary tu- berculosis patients in our department with the occurrence of DILl in anti tuberculosis treatment process. Re- suits the elderly,drinking, hepatitis B virus carriers or a history of liver disease,anti-tuberculosis drug treatment of line 1 -3 weeks, disseminated blood type lung tuberculosis more susceptible to drug-induced liv- er injury. Conclusions early diagnosis of DILl induced by anti- tuberculosis drugs and proper treatment, to ensure that patients can be successfully completed chemotheraov. |
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| Keywords: | Anti tuberculosis drugs liver injury clinical analysis |
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