99mTc-MIBI核素显像诊断甲状腺癌的价值研究

目的研究^99mTc-MIBI核素显像对临床疑似甲状腺癌的诊断价值。方法^99mTc-MIBI及^99mTcO4-显像平行检测106例临床疑似甲状腺癌的甲状腺结节患者，与同期甲状腺彩超和临床病理诊断等进行对照研究。结果^99mTcO2对甲状腺癌诊断灵敏度为82％，特异度为25％，诊断准确度为72％^99mTc-MIBI诊断灵敏度为81％，而特异度上升为75％，诊断准确度达到80％。当^99mTcO4^-诊断甲状腺癌患者为阴性结果时，^99mTc-MIBI对其诊断为阳性的概率却达到了68．18％。结论^99mTc-MIBI显像对甲状腺癌具有一定的定性诊断价值，其可显著提高^99mcO4^-阴性甲状腺癌患者的检出率。

The Diagnostic Value of 99mTc-MIBI Thyroid Scintigraphy for Thyroid Cancer

Objective To investigate the diagnostic value of ^99mTc-MIBI thyroid scintigraphy for suspected thyroid cancer. Methods 106 consecutive patients with the suspected diagnosis of thyroid cancer were scanned by ^99mTc-MIBI and ^99mTcO4^- preoperatively. The results of ultrasound and pathology were analyzed at the same time. Results ^99mTcO4^- thyroid scintigraphy had a sensitivity of 82% and specificity of 25% as a diagnostic test for thyroid cancer. 99mTc-MIBI thyroid scintigraphy had a sensitivity of 81% and specificity of 75%. ^99mTc-MIBI thyroid seintigraphy had higher specificity, and its sensitivity was equal to that of 99mTeO4 . Furthermore,68% thyroid cancer patients with negative ^99mTeO4 could be detected as ^99mTc-MIBI positive. Conclusion These results indicate that ^99mTe-MIBI thyroid scintigraphy,as defined in our study, is a useful method in the assessment of thyroid cancer with a good potential for clinical application.