Natural Killer Activity in Two Cases of Ataxia Telangiectasia |
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| Authors: | H. KASHIWA T. KISHI E. KITTAKA S. HYODO T. KARAKAWA M. OKADA T. MATSUSHITA R. MATSU-URA T. SAKANO K. SAWANO T. USUI |
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| Affiliation: | From the Department of Paediatrics, School of Medicine, Hiroshima University and 1Hiroshima Prefectural Rehabilitation Center for the disabled, Hiroshima, Japan |
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| Abstract: | ABSTRACT. We report two cases of ataxia telangiectasia in which a small number of T cells and a slightly diminished response to phytohaemagglutinin or concanavalin A were observed. In one case, serum IgA was undetectable. In spite of T and/or B cell involvement, natural killer activity and the percentage of natural killer cells determined by monoclonal antibodies Leu 7 were normal in both cases. |
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| Keywords: | ataxia telangiectasia natural killer cells |
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