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Affective Disorders in Mentally Retarded Adolescents —Report of Two Cases with Lithium Treatment—
Authors:Kazuhiko Fukuda  MD    Toshikuni Etoh  MD  Teruo Okuma  MD
Institution:Department of Neuropsychiatry, Tohoku University School of Medicine, Sendai;National Musashi Psychiatric Institute, Tokyo
Abstract:Abstract: Two cases of moderately retarded adolescents with affective disorders have been treated for nine and five years, respectively. Rapid cycling episodes were seen in early adolescence and a long duration of episodes appeared in late adolescence. A two-year lithium therapy was able to control them fairly well but did not work as a prophylaxis. Lithium carbonate induced polydipsia or personality change.
Keywords:affective disorders  mental retardation  adolescence  lithium therapy  polydipsia  rapid cycling episodes
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