| 蚓激酶或阿司匹林预防脑梗死复发的疗效分析 |
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| 引用本文： | 蒋立勤,陈伟.蚓激酶或阿司匹林预防脑梗死复发的疗效分析[J].中国临床药学杂志,2006,15(2):106-107. |
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| 作者姓名： | 蒋立勤 陈伟 |
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| 作者单位： | 1. 上海市虹口区新港社区卫生服务中心内科,上海,200082
2. 上海交通大学新华医院神经内科,上海,200092 |
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| 摘 要： | 目的探讨长期服用蚓激酶或小剂量阿司匹林对脑梗死复发的预防作用。方法对127例脑梗死患者进行回顾性调查,分别统计分析42例(观察组)长期服用蚓激酶(22例,一日120~180U,服药时间>150 d)或小剂量肠溶阿司匹林(20例,一日50~70 mg,服药时间>150 d)的患者及85例(对照组)未正规服用抗凝药物患者的脑梗死复发率。结果脑梗死复发率观察组为9.52%,对照组为30.58%,前者明显低于后者(P<0.05)。结论长期服用蚓激酶或小剂量肠溶阿司匹林对脑梗死复发有一定的预防作用。
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| 关 键 词： | 脑梗死复发 蚓激酶 阿司匹林 |
| 文章编号： | 1007-4406（2006）02-0106-02 |
| 收稿时间： | 2005-10-25 |
| 修稿时间： | 2005-10-25 |
Effect of lumbrukinase or aspirin on prevention of ischemic stroke recurrence |
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| Jiang Liqin,Chen Wei.Effect of lumbrukinase or aspirin on prevention of ischemic stroke recurrence[J].Chinese Journal of Clinical Pharmacy,2006,15(2):106-107. |
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| Authors: | Jiang Liqin Chen Wei |
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| Institution: | 1. Xingang Community Health Service Center, Hongkou District, Shanghai 200082, China ;2. Department of Neurology, Xinhua Hospital, Shanghai Jiaotong University, Shanghai 200092, China |
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| Abstract: | AIM To explore the effect of lumbrukinase(Lum) or small dose of aspirin(Asp) on prevention of ischemic stroke recurrence.METHODS The 127 ischemic stroke patients were retrospectively investigated.Forty-two patients administered with Lum or small dose of Asp and 85 patients without regular use of anticoagulant drugs were compared for observing the recurrence of ischemic stroke.RESULTS The recurrence rate with prevention group was less than that of without preventive drugs(9.52% vs 30.58%).CONCLUSION Lum or small dose of Asp is effective in prevention of ischemic stroke and no ADR are found. |
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| Keywords: | recurrence of ischemic stroke lumbrukinase aspirin |
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