L-ascorbic acid produces hypoglycaemia and hyperinsulinaemia in anaesthetized rats |
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| Authors: | J T Cheng S C Hsieh-Chen C L Tsai |
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| Affiliation: | Department of Pharmacology, College of Medicine, National Cheng Kung University, Taiwan, Republic of China. |
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| Abstract: | L-Ascorbic acid (Vitamin C) produced a marked reduction in the blood glucose concentration following intravenous injection (20-100 mg kg-1) to anaesthetized rats. This hypoglycaemic effect was accompanied by an increase in plasma insulin concentration. D-ascorbic acid produced a similar hypoglycaemic effect. |
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