华东唐松草的化学成分

目的：对华东唐松草（Thalictrum fortunei）化学成分进行分离并鉴别化学结构。方法：利用各种柱色谱方法对其乙醇提取物的正丁醇部位进行分析,用UV、IR、MS、1HNMR、13CNMR等光谱技术鉴定化合物结构。结果：分离鉴定了11个化合物,分别为O-甲基唐松草檗碱（O-methylthalicberine）（1）,24S-lanost-9（11）-ene-3β,16β,24,25,30-pentaol（2）,胆固醇（cholesterol）（3）,β-谷甾醇（β-sitosterol）（4）,豆甾醇（stigmasterol）（5）,豆甾醇3-O-β-D-吡喃葡萄糖苷（stigmasterol3-O-β-D-glucopyranoside）（6）,菠菜甾醇3-O-β-D-吡喃葡萄糖苷（spinasterol3-O-β-D-glucopyranoside）（7）,胡萝卜苷（daucosterol）（8）,蔗糖（sucrose）（9）,邻二苯甲酸正丁酯（palatinolC）（10）,对羟基正丁基酚醚（4-butyloxyphenol）（11）。结论：化合物1-11均为首次从该植物中分离得到。

Chemical Constituents from Thalictrum fortunei

AIM： To study the chemical constituents from the aerial parts of Thalictrumfortunei. METHODS： Various column chromatographic methods were carried out for the isolation and purification of the compounds from the EtOH extract of T. fortunei. Their structures were elucidated by the combined analysis of UV, IR, MS, ^1H and ^13C NMR spectral data. RUSULTS： Eleven compounds were obtained, and their structures were elucidated as O-methylthalicberine （1）, 24S-lanost-9（11）-ene-3β, 16β, 24, 25, 30-pentaol （2）, cholesterol （3）, β-sitosterol （4）, stigmasterol （5）, stigmasterol 3-O-β-D-glucopyranoside （6）, spinasterol 3-O-β-D-glucopyranoside （7）, daucostero （8）, sucrose （9）, palafinol C （10） and 4-butyloxyphenol （11）, respectively. CONCLUSION： All compounds were isolated from this plant for the first time.