| 基于信号处理的SARS病毒的核酸序列的分析 |
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| 引用本文： | 王卫东,刘尚军,范哲意. 基于信号处理的SARS病毒的核酸序列的分析[J]. 医疗卫生装备, 2005, 26(5): 3-5 |
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| 作者姓名： | 王卫东 刘尚军 范哲意 |
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| 作者单位： | 1. 解放军总医院生物医学工程研究室,北京市,100853
2. 北京理工大学电子工程系,北京市,100081 |
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| 摘 要： | 提出了核酸序列所对应的数字信号序列及其自相关序列和互相关序列的离散傅立叶分析方法,并用之对SARS病毒的核酸序列进行了分析。我们发现,SARS病毒的核酸序列具有很强的1/3和2/3频率的周期律。这意味着,SARS病毒具有极强的蛋白质编码能力,很强的变异性。与SARS病毒相比,ADIS病毒(HIV)却仅有1/3频率的周期律,而没有2/3频率的周期律。该差异采用文献犤1犦中的方法是无法观测到的。
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| 关 键 词： | 字符数字转换 自相关 互相关 离散傅立叶变换 |
| 文章编号： | 1003-8868(2005)05-0003-03 |
| 修稿时间： | 2004-09-21 |
SARS virus nucleotide sequence analysis based on signal processing |
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| WANG Wei-dong,LIU Shang-jun,FAN Ze-yi. SARS virus nucleotide sequence analysis based on signal processing[J]. Chinese Medical Equipment Journal, 2005, 26(5): 3-5 |
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| Authors: | WANG Wei-dong LIU Shang-jun FAN Ze-yi |
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| Affiliation: | WANG Wei-dong1,LIU Shang-jun1,FAN Ze-yi2 |
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| Abstract: | This paper puts forward the numerical signal sequence correlated with the nucleotide sequence and the discrete Fourier analysis approach of its self-correlation and cross-correlation sequences. The approach is applied to the analysis of SARS virus nucleotide sequence. It proves that SARS virus nucleotide sequence has the periodicity laws one-third frequency and two-thirds frequency, which means that SARS virus has a strong coding ability and a high variability. Compared to SARS virus, AIDS virus has no the periodic law of two-thirds frequency, but the difference is unobservable by the approach mentioned in reference 1. |
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| Keywords: | conversion of character to number self correlation cross correlation discrete Fourier transformation |
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