胸腔积液临床检验中CEA的应用价值研究

目的 探讨检测血清和胸腔积液中CEA的水平及胸腔积液CEA/血CEA的比值对良、恶性胸腔积液的诊断价值.方法 收集2014年1月至2015年12月本院收治的73例胸腔积液患者为研究对象,根据患者病理检查结果分为良性组(44例)、恶性组(29例),检测并分析两组患者CEA水平及CEA阳性率.结果 恶性组患者血清CEA水平为(137.34±317.22)ng/ml,胸腔积液CEA水平为(264.68±383.87)ng/ml,胸腔积液CEA/血CEA值为(15.62±29.83);良性组血清CEA水平为(4.07±7.67) ng/ml,胸腔积液CEA水平为(2.17±2.97) ng/ml,胸腔积液CEM血CEA值为(0.63±0.35);差异有统计学意义(P＜0.05).恶性组胸腔积液CEA阳性率为79.31％,良性组为6.81％,差异有统计学意义(P＜0.05).结论 癌胚抗原在胸腔积液临床检验中有较高的应用价值,可有效鉴定胸腔积液良恶件.

Study on the application value of CEA in clinical examination of pleural effusion

Objective To investigate the diagnostic value of CEA in serum and pleural effusion and the ratio of pleural effusion CEA / serum CEA in benign and malignant pleural effusion.Methods 73 patients with pleural effusion in our hospital from January 2014 to December 2015 were selected as the research object,and divided into benign group (44 cases) and malignant group (29 cases) according to pathological results of patients.Detected and analyzed the level of CEA and CEA positive rate of two groups.Results The serum CEA level in malignant group was (137.34±317.22) ng/ml,the level of CEA in pleural effusion was (264.68±383.87) ng/ml,the ratio of pleural effusion CEA / serum CEA was (15.62±29.83),those in benign group were (4.07±7.67) ng/ml,(2.17±2.97) ng/ml,(0.63±0.35),with statistically significant differences (P＜0.05).The positive rate of CEA in pleural effusion in malignant group was 79.31％,6.81％ in benign group,with statistically significant difference (P＜0.05).Conclusion The clinical value of carcino-embryonic antigen in the clinical examination of pleural effusion is high,which can effectively identify benign and malignant pleural effusion.