右美托咪定联合氟比洛芬酯在全麻苏醒期躁动预防中的效果评价

目的 评价右美托咪定联合氟比洛芬酯在全麻苏醒期躁动预防中的效果.方法 选取本院收治的130例在全身麻醉下行乳腺癌根治术的患者作为研究对象,分为观察组和对照组.对照组给予右美托咪定,观察组在对照组的基础上联合使用氟比洛芬酯.结果 观察组拔管后5 min平均动脉压为(91.63±8.86)mmHg(1 mmHg=0.133 kPa),对照组为(103.58±9.67)mmHg;观察组苏醒时间为(11.52±2.76)min,对照组为(17.52±3.68) min;观察组镇静躁动发生1例,占比1.53％,对照组镇静躁动发生8例,占比12.31％;差异均有统计学意义(P＜0.05).结论 在对患者手术治疗过程中,采用右美托咪定联合氟比洛芬酯预防患者全麻苏醒期的躁动,能够有效平稳患者的平均动脉压和心率,缩短患者拔管和苏醒时间,并对患者的苏醒期躁动具有一定的预防作用,能够广泛应用于临床医学中.

Dexmedetomidine combined with flurbiprofen axetil in prevention of agitation during anesthesia recovery period

Objective To evaluate the effect of dexmedetomidine combined with flurbiprofen axetil in the prevention of agitation during anesthesia recovery period.Methods 130 breast cancer patients treated at our hospital were selected as study objects and divided into an observation group and a control group.The control group were given dexmedetomidine and the observation group dexmedetomidine and flurbiprofen.Results The mean arterial pressure 5 min after extubation and the recovery time were (91.63±8.86) mmHg (1 mmHg=0.133 kPa) and (11.52±2.76) min in the observation group and were (103.58±9.67) mmHg and (17.52±3.68) min in the control group (P＜0.05).1 case (1.53％) got agitation in the observation group and 8 (12.31％) in the control group (P＜0.05).Conclusions Dexmedetomidine combined with flurbiprofen axetil in the prevention of agitation during anesthesia recovery period is effective and can make the patients' mean artery pressure and heart rate stable and shorten extubation time and recovery time,so it is worth being clinically generalized.