Long-term oral treatment of urinary tract infections with single daily doses of a new antibacterial drug combination (Kelfiprim) |
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Authors: | W von Niederhäusern J-J Boillat Dr D Petrescu W Groppi A Fanfani V Mandelli |
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Institution: | 1. Service de Chirurgie, Département d'Urologie, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland 2. Therapeutic Research Department, Farmitalia Carlo Erba, Milan, Italy 3. R & D Biometry, Farmitalia Carlo Erba, Milan, Italy
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Abstract: | Of 30 patients with severe, complicated U.T.I. 27 have been given single daily doses of Kelfiprim (KP), a new sulfatrimethoprim combination, for 8 weeks. In 24 bacteriuria was lastingly controlled, one had a relapse, one had a reinfection, and in one, with bladder carcinoma, bacteriuria persisted. Three other patients received KP for shorter periods, as they presented gastric intolerance or skin hypersensitivity, but in two of them a lasting sterilization of the urine has been obtained. The usefulness of a single daily dose schedule is stressed. |
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