小细胞肺癌内窥镜、病理学及免疫组织化学研究

 目的 研究218 例肺小细胞癌的纤维支气管镜、临床病理及免疫组织化学特征。方法 分析纤维支气管镜、病理特征并选择80 例作免疫组织化学观察。结果 纤维支气管镜检以不规则结节状隆起物和管腔狭窄最为常见。80 例免疫组织化学染色结果显示： CK69 例、EMA74例、NSE72 例、5-HT56 例呈阳性反应, 表明它们向上皮和神经内分泌方向分化。结论 肺小细胞癌向上皮和神经内分泌方向分化, 表明肺小细胞癌来自多能干细胞。

A Study on Fiberbronchoscope, Clinicopathology and Immunohistochemistry of Lung Small Cell Carcinoma

Objective This paper study the clinical pathology、fiberbronchoscope、immunohistochemistry characterstic of small cell cancer of lung which amount to 218 cases.Among them there are 186 cases of male,and female 32 cases,the age of patients are from 29 years to 74 years.Methods analyse the fiberbronchoscope and pathological character,and select 80 case to accomplish the immunohistochemical study.Reaults the fiberbronchoscope show irregular nodular knurl and cavity is most common.eighty immunochemical stain result indicate:CK 64、EMA 74、 NSE 72、5-HT 56 cases are demonstrated positive reaction,indicate that they are differentiated toward epithelial and neuroendocrine Conclusion small cell carcinoma of lung is differentiated toward epithelial and neuroendocrine,this prove the small cell cancer of lung is generated from multi potent stem cell