浅表食管癌侵袭深度及分化程度与区域淋巴结转移的临床分析

目的探讨浅表食管癌侵袭深度及分化程度与区域淋巴结转移的关系。方法本院2002年6月至2004年6月总共手术治疗食管癌923例,其中早期浅表食管癌68例,本文就对其术后侵袭深度及分化程度与区域淋巴结转移情况进行回顾性分析。结果本组无手术死亡,全组淋巴结转移率27%,其中高出黏膜型食管癌的淋巴结转移率为38%,侵袭越深,淋巴结转移率越高;分化程度越低淋巴结转移率越高。结论高度重视浅表型食管癌的根治性,对早期食管癌也应按肿瘤外科的原则行食管的次全切除术并常规清扫区域淋巴结。

The relationship of macroscopic shape of superficial esophageal carcinoma to depth of invasion and histologic differentiation features and regional lymph node metastasis

Objective To study the relationship shape of superficial esophageal carcinoma between the depth of invasion(T)and regional lymph node metastasis(N),the histologic differentiation and N.Methods A retrospective review of 68 consecutive patients undergone esophageal resection was conducted to define the relationship between T and N,histologic differentiation and N.Results There was no death in our group.The regional lymph node metastasis was 27%,and once invaded overtopping the mucosa layer was 38%.It was invaded the more depth and the lower histologic differentiation,regional lymph node metastasis increased significantly.Conclusion For patients with superficial esophageal carcinoma,T and histologic differentiation are important predictors of N and those association play an important role in clinical staging and treatment decisions.It is important to clear lymph nodes and treat with comprehensive therapy after radical cure operation of the superficial esophageal carcinoma in order to improve curative effect.