呼吸系统感染病原菌种类及耐药分析

目的 了解近期呼吸系统感染病原菌的种类和耐药趋势,指导临床合理用药。方法 对2000年1月-2002年12月在我院就诊(门诊和住院)病人的痰或咽分泌物标本进行常规分离鉴定,药敏试验采用K-B法,超广谱β-内先胺酶(ESBLs)的检测采用美国2001年1月颁布的确认试验标准。结果 848份标本中分离出致病菌或条件致病菌416株,其中革兰氏阴性杆菌195标,占47％,ESBLs阳性57株;酵母样真菌112株,占27％;革兰氏阳性球菌109株,占26％。结论 呼吸系统感染的病原菌以革兰氏阴性杆菌为主,其次为酵母样真菌。革兰氏阴性杆菌中ESBLs阳性菌株的种类和数量呈上升趋势,应加强对产ESBLs菌株的检测,指导临床合理使用抗生素,防止耐药菌株的产生。

Analysis of kinds and antibiotic resistance of pathogenic in respiratory system infection

Objective To investigate the kind of pathogenic bacteria and their tendency of antibiotics resistance in recent respiratory system infection, and to conduct clinical - doctor to use medicine reasonably. Methods: All specimens came from outpatients and inpatients from January 2000 to December 2002. The pathogenic bacteria were isolated and identified routinely from the patient's phlegm and pharynx secretion. K - B method was used and the American testing standard issued in January 2001 was adopted of testing Extent - spectrum betd- lactamases(ESBLs). Result :416 are isolated from 848 cases, including G bacillus 195(47% , 57 cases' sESBLs are positive), yeast fungus 112(27%)and G+ coccus 109(26%). Conclusion: The G bacillus is the most bateria in all pathogenic bacteria in respiratory system infection. The second is yeast fungus. The kind and quantity of pathogenic bacteria which produce ESBls are more in G bacillus. They must be tested emphatically so as to conduct clinical - doctor to use the antibiotics reasonably and avoid resistant germs being produced.