Reserpine,hydrochlorothiazide and pituitary-gonadal hormones in hypertensive patients |
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| Authors: | T. W. Boyden C. A. Nugent T. Ogihara T. Maeda |
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| Affiliation: | (1) Department of Internal Medicine, Veterans Administration Medical Center, and the University of Arizona Health Sciences Center, 85724 Tucson, Arizona, USA;(2) Present address: Department of Medicine and Geriatrics, Osaka University Medical School, Osaka, Japan;(3) Present address: Department of Internal Medicine, Tokyo Women's Medical College, Tokyo, Japan |
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| Abstract: | Summary Sex histories and serum samples were obtained from 27 hypertensive men before and after 3 months of therapy with either 100 mg of hydrochlorothiazide or 0.25 mg of reserpine daily. Sera were analyzed for testosterone, dihydrotestosterone, estradiol, luteinizing hormone and prolactin. Both drugs effectively lowered blood pressure. The incidence of impaired sexual performance was low and insignificantly different in the two treatment groups. There were no significant changes in serum hormone concentrations as a result of drug therapy. |
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| Keywords: | reserpine hydrochlorothiazide pituitary hormones gonadal hormones hypertension serum concentration antihypertensive therapy |
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