| 1-乙基-6-氟-1,4-二氢-4-氧-7-(4-对硝基苯甲酰基-1-哌嗪基)喹啉-3-羧酸及其类似物的合成 |
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| 引用本文： | 陈恒昌,郭彦春,路德让.1-乙基-6-氟-1,4-二氢-4-氧-7-(4-对硝基苯甲酰基-1-哌嗪基)喹啉-3-羧酸及其类似物的合成[J].药学学报,1991,26(4):299-302. |
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| 作者姓名： | 陈恒昌 郭彦春 路德让 |
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| 作者单位： | 郑州大学化学系,郑州450052 |
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| 摘 要： |
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| 关 键 词： | 氟哌酸 类似物 合成 |
| 收稿时间： | 1989-06-19 |
SYNTHESES OF 1-ETHYL-6-FLUORO-1,4-DIHYDRO-4-OXO-7-[(4-P-NITROBENZOL)-1-PIPERAZINYL] QUINOLINE-3-CARBOXYLIC ACID AND ITS ANALOGUES |
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| HC Chen YC Guo and DR Lu.SYNTHESES OF 1-ETHYL-6-FLUORO-1,4-DIHYDRO-4-OXO-7-[(4-P-NITROBENZOL)-1-PIPERAZINYL] QUINOLINE-3-CARBOXYLIC ACID AND ITS ANALOGUES[J].Acta Pharmaceutica Sinica,1991,26(4):299-302. |
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| Authors: | HC Chen YC Guo and DR Lu |
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| Institution: | Department of Chemistry, Zhengzhou University. |
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| Abstract: | Syntheses of thirteen new compounds of 1-ethyl-6-flouro-1, 4-dihydro-4-oxo-7-(4-p-nitrobenzoyl)1-piperazinyl] quinoline-3-carboxylic acid and its analogues are reported. The structures were determined by IR, 1HNMR and elemental analysis. Four compounds have been subjected to antibacterial activity tests in vitro. Compound I1 was shown to have significant activity. |
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| Keywords: | Pyridonecarboxylic acids Quinoline derivatives Antibacterial agents |
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