青年人冠心病临床、冠状动脉造影特点及介入治疗

目的 探讨青年冠心病的临床冠状动脉造影特点及介入治疗的效果。方法 对52例年龄≤40岁临床诊断冠心病的患者行冠状动脉造影检查,分析其临床及冠状动脉造影特点。28例患者进行了经皮冠状动脉腔内血管成形术(PTCA)。结果 冠心病的危险因素中吸烟占85.7％,高胆固醇血症占46.2％,冠心病家族史占38.5％;发病前有明显诱因者占55.8％;冠状动脉造影未见明显异常者占7.7％,单支、双支、三支病变者分别为57.7％,21.2％,13.5％;行介入治疗的28例患者共扩张血管37支,病变45处,置入支架41枚;病例成功率96.4％,病变成功率93.4％。结论 青年人冠心病主要危险因素为男性、吸烟、高胆固醇血症、冠心病家族史.单支血管病变为主,发病前多有明显诱因,PTCA是一种安全有效的介入性治疗技术。

Clinical characters ,coronary angiographic finding and intervention outcome in young patients with coronary artery disease

Objective To study the clinical characters,coronary angiographic finding and intervention outcome of patients under 40 years old. Methods Among the 52 young patients undergoing coronary angiography, there were 48 males and 4 females with a mean age of 35. 8±4. 1 (28-40) years. The clinical signs were studied, percutenous transluminal coronary angioplasty (PTCA ) was performed in 28 patients. Results The most frequent risk factors documented in this study in descending order were smoking (85. 7%), high level of total blood cholesterol (46. 2%), family history of coronary artery disease (38. 5%). Angiography showed the prevalence rate of one, two, and three vessel disease was 57. 7% , 21. 2% ,13. 5% , respectively. PTCA was performed in 28 patients with 37 diseased vessels and 45 lesions, 41 stents were implanted into 23 LAD, 7 stents into LCX, and 11 stents into RCA, the clinical (patient ) and technical (vessel)success rate was 96. 4% , 93. 4% .respectively. Conclusion The main risk factors of young patients with coronary artery disease, (CAD) were male, cigarette smoking, high level of total blood cholesterol and family history of CAD a high percentage of single-vessel disease, and certain predisposing factors appear to be present prior to the onset of symptoms in most patients. PTCA is an effective and relatively safer intervention procedure for young patients with CAD.