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炎症性肠病发病机制的研究进展
引用本文:曹婷婷,薛原,曲波. 炎症性肠病发病机制的研究进展[J]. 胃肠病学和肝病学杂志, 2012, 21(2): 110-113
作者姓名:曹婷婷  薛原  曲波
作者单位:哈尔滨医科大学附属第二医院消化内科,黑龙江哈尔滨,150001
摘    要:炎症性肠病(inflammatory bowel disease,IBD)主要包括克罗恩病(crohn’s disease,CD)和溃疡性结肠炎(ulcerative colitis,UC),是一组以持续性肠道炎症为特征的疾病。其确切的发病机制尚不十分明确,一般认为是环境因素作用于遗传易感的个体,使其免疫系统发生过度的免疫反应,最终导致肠道炎症。

关 键 词:炎症性肠病  发病机制  环境因素  遗传因素  免疫因素

The advance in studies of the pathogenesis of inflammatory bowel disease
CAO Tingting , XUE Yuan , QU Bo. The advance in studies of the pathogenesis of inflammatory bowel disease[J]. Chinese Journal of Gastroenterology and Hepatology, 2012, 21(2): 110-113
Authors:CAO Tingting    XUE Yuan    QU Bo
Affiliation:Department of Gastroenterology,the 2nd Affiliated Hospital of Harbin Medical University,Harbin 150001,China
Abstract:The inflammatory bowel disease(IBD),mainly consisting of Crohn’s disease(CD) and ulcerative colitis(UC),is characterized by persistent intestinal inflammation.Although the exact pathogenesis of IBD is unknown,it is generally accepted that the uncontrolled immune response leads to intestinal inflammation with the effect of environmental factor in genetically predisposed individuals.
Keywords:Inflammatory bowel disease  Pathogenesis  Environmental factor  Genetic factor  Immunological factor
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