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Hedgehog信号通路与胃疾病研究进展
引用本文:黄利,彭琼,甘惠中. Hedgehog信号通路与胃疾病研究进展[J]. 胃肠病学和肝病学杂志, 2012, 21(2): 193-196
作者姓名:黄利  彭琼  甘惠中
作者单位:安徽医科大学第三临床学院合肥市第一人民医院消化内科,安徽合肥,230061
摘    要:Hedgehog(Hh)信号通路是人类胚胎发育时的重要信号通路,在成熟个体,可能与维持胃部正常功能有关。研究显示Hh信号与H.pylori相关性胃炎、肠化及胃癌等疾病有关。本文就Hh信号通路与胃部疾病的关系的研究进展作一综述。

关 键 词:Hedgehog  信号通路  胃疾病

Advances in research on relationship between Hedgehog signaling pathway and stomach diseases
HUNG Li , PENG Qiong , GAN Huizhong. Advances in research on relationship between Hedgehog signaling pathway and stomach diseases[J]. Chinese Journal of Gastroenterology and Hepatology, 2012, 21(2): 193-196
Authors:HUNG Li    PENG Qiong    GAN Huizhong
Affiliation:Department of Gastroenterology,Third Affiliated Hospital of Anhui Medical University,Hefei 230061,China
Abstract:Hedgehog(Hh) signaling pathway,which plays a critical role in human embryonic development,may be important for homeostasis of the adult stomach.Researches reveal that Hh signal is related with H.pylori-associated gastritis,intestinal metaplasia and stomach cancer.This review focused on the progress of Hh in stomach diseases.
Keywords:Hedgehog  Signaling pathway  Stomach disease
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