| IP-10和CXCR3与消化系统肿瘤 |
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| 引用本文： | 孟欣颖,周长宏. IP-10和CXCR3与消化系统肿瘤[J]. 胃肠病学和肝病学杂志, 2012, 21(5): 488-490 |
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| 作者姓名： | 孟欣颖 周长宏 |
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| 作者单位： | 青岛市市立医院干保二科,山东青岛,266071 |
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| 摘 要： | 干扰素诱导蛋白10(IFN-γ-inducible protein,IP-10)是由干扰素-γ和/或脂多糖诱导产生的一类可以趋化淋巴细胞的蛋白质,又称CXC趋化因子配体10(CXCL10)。趋化因子CXC受体3(CXCR3)是IP-10的受体。近年来趋化因子及其受体在肿瘤免疫中的作用备受重视,本文就IP-10和CXCR3在消化系统肿瘤中的研究进展作一综述。
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| 关 键 词： | IP-10 CXCR3 消化道肿瘤 |
IP-10/CXCR3 and gastrointestinal tract cancer |
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| MENG Xinying , ZHOU Changhong. IP-10/CXCR3 and gastrointestinal tract cancer[J]. Chinese Journal of Gastroenterology and Hepatology, 2012, 21(5): 488-490 |
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| Authors: | MENG Xinying ZHOU Changhong |
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| Affiliation: | Department of Health Care,Qingdao Municipal Hospital(East),Qingdao 266071,China |
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| Abstract: | IFN-γ-inducible protein 10(IP-10),also called CXC chemokines ligand 10(CXCL10),is a kind of protein stimulated by interfrron-γ and/or lipopolysaccharide with the chemotactic effects to lymphpcytes.CXCR3 is the only receptor of IP-10.Chemokines and their receptors play important roles in the tumor immunity.We reviewed the advances in IP-10/CXCR3 and gastrointestinal tract cancer. |
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| Keywords: | IP-10 CXCR3 Gastrointestinal tract cancer |
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