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Th17细胞在炎症性肠病发病机制作用的研究进展
引用本文:关家喜,周宇.Th17细胞在炎症性肠病发病机制作用的研究进展[J].胃肠病学和肝病学杂志,2012,21(2):114-117.
作者姓名:关家喜  周宇
作者单位:广东医学院附属医院消化内科,广东湛江,524001
摘    要:炎症性肠病的病因和发病机制尚未完全明确。最近的研究表明,Th17细胞及与其相关的细胞因子、Th细胞亚群所导致的炎症过程在炎症性肠病的发生发展中起重要作用。本文就Th17的分化调控机制及Th17与其相关的细胞因子、Th细胞亚群在炎症性肠病的发病机制中的作用作一概述。

关 键 词:炎症性肠病  发病机制  Th17细胞

Development of Th17 in the pathogenesis of inflammatory bowel disease
GUAN Jiaxi , ZHOU Yu.Development of Th17 in the pathogenesis of inflammatory bowel disease[J].Chinese Journal of Gastroenterology and Hepatology,2012,21(2):114-117.
Authors:GUAN Jiaxi  ZHOU Yu
Institution:Department of Gastroenterology,the Affiliated Hospital of Guangdong Medical College,Zhanjiang 524001,China
Abstract:The etiology and pathogenesis of inflammatory bowel disease(IBD) remain incompletely understood.More recent studies have shown that Th17,Th17-related cytokines and Th17-related Th cell population play important roles in the pathogenesis of IBD.This article reviewed the regulation of Th17 differentiation and the pathogenesis of inflammatory bowel disease caused by Th17,Th17-related cytokines and Th17-related T help cell population.
Keywords:Inflammatory bowel disease  Pathogenesis  T help 17 cell
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