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注射用盐酸头孢吡肟处方研究
引用本文:陈振阳,周翔,冼见成,王磊.注射用盐酸头孢吡肟处方研究[J].现代食品与药品杂志,2006,16(1):52-54.
作者姓名:陈振阳  周翔  冼见成  王磊
作者单位:深圳市制药厂 广东深圳518029
摘    要:目的确定注射用盐酸头孢吡肟中L-精氨酸的加入量。方法向适量盐酸头孢吡肟中加入L-精氨酸的量分别为:350、550、650、700、710、720、725、730、740、750、800、900 mg,分别考察其pH值、颜色和澄清度。结果加入L-精氨酸的最佳范围为720~730 mg。结论确定我厂注射用盐酸头孢吡肟中L-精氨酸的加入量为每1 g头孢吡肟中加入L-精氨酸725 mg。

关 键 词:注射用盐酸头孢吡肟  L-精氨酸  处方
文章编号:1673-4610(2006)01-0052-03
收稿时间:2005-04-26
修稿时间:2005-07-23

Study on the formulation of Cefepime Dihydrochloride for Injection
CHEN Zhen-yang,ZHOU Xiang,XIAN Jian-cheng,WANG Lei.Study on the formulation of Cefepime Dihydrochloride for Injection[J].JOurnal of Modern Food and Pharmaceuticals,2006,16(1):52-54.
Authors:CHEN Zhen-yang  ZHOU Xiang  XIAN Jian-cheng  WANG Lei
Abstract:Objective To confirm the quantity of L-Arginine added to Cefepime Dihydrochloride fer injection. Method Add respectively 350,550,650,700,710,720,25,730,740,750,800,900 mg L-Arginine to 1 g Cefepime Dihydrochloride for injection, and examine the pH.color and clarity. Result The prime range of quantity of L-Arginine added to 1 g Cefepime Dihydrochloride for injection is 720-730 mg. Conclusion Decide to add 725 mg L-Arginine to 1 g Cefepime Dihydrochloride for injection manufactured by our factory.
Keywords:Cefepime Dihydrochloride for Injection  L-Arginine  Formulation
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