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Intracardiac thrombus in Behçet's disease. A report of three cases
作者姓名:Ben Ghorbel I  Ibn Elhadj Z  Khanfir M  Braham A  Fekih M  Drissa H  Houman MH
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收稿时间:16 January 2004

Thrombus intracardiaque au cours de la maladie de Behçet: À propos de trois cas
Ben Ghorbel I,Ibn Elhadj Z,Khanfir M,Braham A,Fekih M,Drissa H,Houman MH.Thrombus intracardiaque au cours de la maladie de Beh?et: à propos de trois cas[J].Journal des Maladies Vasculaires,2004,29(3):159-161.
Authors:Ben Ghorbel I  Ibn Elhadj Z  Khanfir M  Braham A  Fekih M  Drissa H  Houman M H
Institution:1. Service de médecine interne;2. Service de cardiologie adulte, Hôpital La Rabta, 1007 Tunis, Tunisie;1. Médecine vasculaire, hôpital Édouard-Herriot, hospices civils de Lyon, 5, place d’Arsonval, 69003 Lyon, France;2. Chirurgie vasculaire, hôpital Édouard-Herriot, hospices civils de Lyon, 69003 Lyon, France;3. Angiologie-phlébologie et médecine vasculaire, hôpital privé Jean-Mermoz, 69008 Lyon, France;4. Laboratoire d’anatomie et cytologie pathologiques, hôpital Édouard-Herriot, hospices civils de Lyon, 69003 Lyon, France;1. Université Paris Descartes, 75014 Paris, France;2. Centre Cochin ambulatoire d’ophtalmologie, groupe hospitalier Cochin–Hôtel-Dieu, 27, rue du Faubourg-Saint-Jacques, 75014 Paris, France
Abstract:Intracardiac thrombus formation is exceptional in Behçet's disease (less than 50 cases had been reported). Among 180 patients with Behçet's disease (according to the criteria of the international study group for Behçet's disease), three were diagnosed as having intracardiac thrombus. All were male, the mean age at the time of the diagnosis of the intracardiac thrombus was 27 years and the mean disease duration was 4.8 years. The presenting symptom was hemoptysis in two patients and heart failure in the third. Surgery was the first attempted treatment in two patients but thrombus recurred and resolved after medical treatment. The third patient was given corticosteroids and anticoagulants as the first line treatment. The thrombus did not resolve and the patient declined surgery.Intracardiac thrombus formation should be considered when a young Behçet's disease patient presents with an intracardiac mass. Medical treatment including corticosteroids, immunosuppressive drugs and anticoagulants should be considered as the first line treatment and surgery should be considered when there is no resolution of the thrombus or when it becomes massive and extensive. In certain cases, thrombolytic treatment becomes an interesting alternative to surgery.
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