| 不同产地红景天破壁饮片、破壁粉体和传统饮片HPLC指纹图谱相关性研究 |
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| 引用本文： | 方碧烟,甘均龙,史军杰,彭丽华,陈炜璇,成金乐. 不同产地红景天破壁饮片、破壁粉体和传统饮片HPLC指纹图谱相关性研究[J]. 现代中药研究与实践, 2021, 35(1): 33-37 |
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| 作者姓名： | 方碧烟 甘均龙 史军杰 彭丽华 陈炜璇 成金乐 |
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| 作者单位： | 广州中医药大学中药资源科学与工程研究中心,广东广州510006;国家中医药管理局中药破壁饮片技术与应用重点研究室,中山市中智药业集团有限公司,广东中山528437;岭南中药资源教育部重点实验室(广州中医药大学),广东广州510006;国家中成药工程技术研究中心南药研发实验室,广东广州510006;国家中医药管理局中药破壁饮片技术与应用重点研究室,中山市中智药业集团有限公司,广东中山528437 |
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| 基金项目： | 中山市中药破壁饮片技术与应用协同创新中心(2016C1014)。 |
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| 摘 要： | 目的 建立红景天破壁饮片(UGP)、破壁粉体(UP)及传统饮片(DP)的HPLC指纹图谱及其分析方法,为全面评价红景天破壁饮片的质量提供参考.方法 通过HPLC采集10批次红景天传统饮片、破壁粉体及破壁饮片的指纹图谱,并对其进行相似度评价、主成分分析(PCA)和系统聚类分析(HCA).结果 建立了红景天破壁饮片、破壁粉...
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| 关 键 词： | 红景天 传统饮片 破壁粉体 破壁饮片 指纹图谱 不同产地 |
Correlation Study on HPLC Fingerprints of Ultrafine Granular Powder,Ultrafine Powder and Decoction Pieces of Rhodiolae Crenulatae Radix et Rhizoma from Different Habitats |
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| FANG Bi-yan,GAN Jun-long,SHI Jun-jie,PENG Li-hua,CHEN Wei-xuan,CHENG Jin-le. Correlation Study on HPLC Fingerprints of Ultrafine Granular Powder,Ultrafine Powder and Decoction Pieces of Rhodiolae Crenulatae Radix et Rhizoma from Different Habitats[J]. Research and Practice on Chinese Medicines, 2021, 35(1): 33-37 |
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| Authors: | FANG Bi-yan GAN Jun-long SHI Jun-jie PENG Li-hua CHEN Wei-xuan CHENG Jin-le |
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| Affiliation: | (Research Center of Chinese Herbal Resource Science and Engineering,Guangzhou University of Chinese Medicine,Guangzhou 510006,China;Key Laboratory of Technologies and Applications of Ultrafine Granular Powder of Herbal Medicine,State Administration of Traditional Chinese Medicine Zhongshan Zhongzhi Pharmaceutical Group Co.,Ltd.,Zhongshan 528437,China;Key Laboratory of Chinese Medicinal Resource from Lingnan(Guangzhou University of Chinese Medicine),Ministry of Education,Guangzhou 510006,China;Joint Laboratory of National Engineering Research Center for the Pharmaceutics of Traditional Chinese Medicines,Guangzhou 510006,China) |
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| Abstract: | Objective To establish HPLC fingerprints of ultrafine granular powder(UGP),ultrafine powder(UP) and decoction pieces(DP) of Rhodiolae Crenulatae Radix et Rhizoma(Rhodiola) for providing reference for quality evaluation of UGP of Rhodiola.Methods Collected 10 batches of DP,UP,UGP of Rhodiola fingerprints by HPLC.And analyze the fingerprints by similarity evaluation,principal component analysis(PCA)and hierarchical cluster analysis(HCA).Results HPLC fingerprints of UGP,UP and DP of Rhodiola are established,and 18 common peaks are marked.The similarity of the same batch of UGP,UP and DP of Rhodiola are all more than 0.99.Rhodiola samples from different habitats could be divided into three categories by?PCA and HCA.Conclusion The established fingerprint analysis method is stable,reliable and repeatable.It can provide reference for the quality control and evaluation of UGP of Rhodiola combined. |
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| Keywords: | Rhodiolae Crenulatae Radix et Rhizoma decoction pieces ultrafine powder ultrafine granular powder fingerprint different habitats |
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