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Desmethyl Macrolides: Synthesis and Evaluation of 4-Desmethyl Telithromycin |
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| Authors: | Ian Glassford,Miseon Lee,Bharat Wagh,Venkata Velvadapu,Tapas Paul,Gary Sandelin,Charles DeBrosse,Dorota Klepacki,Meagan C. Small,Alexander D. MacKerell,Jr., Rodrigo B. Andrade | |
| Affiliation: | †Department of Chemistry, Temple University, Philadelphia, Pennsylvania 19122, United States;‡Center for Pharmaceutical Biotechnology, Universityof Illinois, Chicago, Illinois 60607, UnitedStates;§Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland 21201, United States | |
| Abstract: | ||
| Keywords: | Total synthesis ketolide antibiotics antibioticresistance telithromycin molecular modeling desmethyl analogues | |