镇静治疗对手术后重症患者使用机械通气的影响

目的探讨手术后ICU患者行机械通气时镇静治疗的临床应用价值。方法 120例术后需机械通气的ICU患者随机分为两组,A组为镇静组(80例),B组为对照组(40例)。A组又分为A1组40例,用咪唑安定镇静;A2组40例,用丙泊酚镇静;B组不用镇静剂。观察比较A、B两组患者术前、术毕、停机械通气前、停机后2h的临床表现、生命体征和机械通气治疗时间等。结果 A组患者少有恐惧感,脱机时血压、心率平稳;B组患者诉不适较多,脱机时血压、心率均明显升高(P<0.01);B组使用机械通气治疗时间较A组延长,两组间比较有显著性差异(P<0.01)。结论应用镇静剂使手术后机械通气的患者处于浅睡眠状态,能减少恐惧,缩短机械通气治疗时间。

Sedative effect on mechanical ventilation in post-operative patients in critical illness

Objective To discuss the value of sedative effect on mechanical ventilation patients after operations in ICU.Methods 120 post-operative patients in ICU who needed mechanical ventilation were randomly were divided into two groups,80 patients in therapy group A,40 patients in control group B.And patients in group A randomly were divided into midazolam group A1 and propofol group A2,40 patients in each group.None of group B was sedated.To compare patients’ symptoms,complaints,MAP,RR,HR,and time course of mechanical ventilation.Results The MAP,RR and HR of the patients in group A were kept steady,few of the groups felt uncomfortable or fear （P〈0.01）,the mechanical ventilation time of this group was shorter than that of group B （P0.01）.Conclusion To sedate post-operative patients who needs mechanical ventilation in an ideal sedation level can maintain comfort and reduce the time course of mechanical ventilation.