Verbal scales in the acute treatment of migraine: semantic categories and clinical relevance |
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Authors: | H Massiou C Tzourio M El Amrani MG Bousser |
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Affiliation: | Department of Neurology, Hôpital Saint-Antoine, Paris, France |
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Abstract: | Verbal scales are currently used as efficacy parameters in acute migraine trials. In order to determine the correlation between headache intensity, functional disability, and relevant pain reduction, 100 patients completed a questionnaire. Our results showed that a verbal scale of headache intensity alone has different implications from one that includes pain intensity and functional ability. The reduction from a moderate to a mild headache was satisfactory to only 15% of the patients. In contrast, 77% of patients were satisfied when the headache intensity was reduced from severe to mild. These findings imply that, in assessing the efficacy of drugs used for migraine, a redaction in pain intensity from moderate to mild should not be considered as a good outcome. |
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Keywords: | Clinical trials four-point verbal rating scale functional disability scale migraine |
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