New aspects of the clinicopathological features and treatment of mycosis fungoides and Sézary syndrome |
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| Authors: | Masutaka Furue Takafumi Kadono |
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| Affiliation: | 1. Department of Dermatology, Kyushu University, Fukuoka, Japan;2. Department of Dermatology, St Marianna University School of Medicine, Kanagawa, Japan |
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| Abstract: | Mycosis fungoides and Sézary syndrome are T‐helper (Th)2‐skewed cutaneous lymphomas. The clinical course of mycosis fungoides is classically indolent, manifesting as patches, plaques and tumors. Along with their progression, Th2 dominance tends to be accelerated. In this review, we discuss the epidemiology, clinicopathogenetic features and therapeutic approaches in mycosis fungoides and Sézary syndrome. |
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| Keywords: | chemokine mycosis fungoides pathogenesis Sé zary syndrome treatment |
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