| N-末端脑钠肽前体对急性呼吸困难鉴别诊断价值的探讨 |
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| 引用本文： | 黄梅女,吴梅芳,许开祖,吴国盛.N-末端脑钠肽前体对急性呼吸困难鉴别诊断价值的探讨[J].现代保健,2014(4):100-101. |
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| 作者姓名： | 黄梅女 吴梅芳 许开祖 吴国盛 |
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| 作者单位： | 莆田学院附属医院,福建莆田351100 |
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| 摘 要： | 目的：探讨N-末端脑钠肽前体（NT-proBNP）对急性呼吸困难鉴别诊断的价值。方法：将200例急性呼吸困难患者分为心源性呼吸困难组和肺源性呼吸困难组，分别测定其血浆NT-proBNP浓度。结果：心源性呼吸困难组的血浆NT-proBNP浓度明显高于肺源性呼吸困难组，两组比较差异有统计学意义（P〈0.05）；心源性呼吸困难组的血浆NT-proBNP浓度在心功能不同级别间差异有统计学意义（P〈0.05）。结论：NT-proBNP浓度对于鉴别心源性呼吸困难和肺源性呼吸困难具有显著的临床意义，可作为鉴别急性呼吸困难病因的一个客观指标。
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| 关 键 词： | N-末端脑钠肽前体 心力衰竭 呼吸困难 |
The Value of NT - proBNP in the Differential Diagnosis of Acute Dyspnea |
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| Institution: | /HUANG Mei-nv, WU Mei-fang, XU Kai-zu, et al( The Affiliated Hospital of Putian University, Putian 351100, China) |
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| Abstract: | Objective：To study the value of N - terminal pro-biain natriuretic peptide（NT-proBNP）in the differential diagnosis of acute dyspnea. Method：200 patients with acute dyspnea were divided into two groups：100 patients with heart disease and 100 patients with pulmonary disease. The level of NT-proBNP was measured. Result：The level of NT-proBNP in patients with dyspnea caused by heart disease was obviously higher than those patients with dyspnea caused by pulmonary disease,there were significant differences between the two groups（P〈0.05）. The level of NT-proBNP in patients with different classes of the NYHA heart function was also significantly different（P〈0.05）. Conclusion：NT-proBNP which has remarkable clinical significance can be used as the indicator in the differential diagnosis of acute dyspnea. |
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| Keywords: | N-terminal pro-brain natriuretic peptide Heart failure Dyspnea |
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