小剂量舒芬太尼联合丙泊酚用于无痛人工流产术的效果观察

目的:研究丙泊酚联合芬太尼或小剂量舒芬太尼在无痛人工流产术中的临床效果及安全性。方法:选取2012年5月-2013年5月本院行无痛人工流产术的60例患者,按照随机数字表法将其分为试验组和对照组各30例,试验组采用舒芬太尼联合丙泊酚麻醉,对照组使用芬太尼联合丙泊酚麻醉。记录两组患者生命体征变化、麻醉时间、苏醒时间及丙泊酚用量,并观察其恶心、呕吐、术后宫缩痛等不良反应情况。结果:两组患者术中5 min的MAP、HR、SpO2等指标与术前相比均有明显下降,比较差异均有统计学意义(P0.05);但两组患者的各生命体征指标比较差异无统计学意义(P0.05)。试验组麻醉时间、苏醒时间均明显短于对照组,且试验组丙泊酚用量较对照组明显减少,比较差异均有统计学意义(P0.05)。两组患者恶心呕吐发生情况比较差异无统计学意义(P0.05),但试验组术后宫缩痛例数明显少于对照组,差异有统计学意义(P0.05)。结论:小剂量舒芬太尼联合丙泊酚用于无痛人工流产术后,增加了手术的安全性和疗效,更值得在临床中推广应用。

Effect Observation of Painless Abortion with Small Doses of Sufentanil and Propofol

Objective：To research propofol combined fentanyl or small doses sufentanil in clinical effect and safety of painless induced abortion operation.Method：Sixty patients with painless induced abortion operation were selected in our hospital from May 2012 to May 2013,they were randomly divided into the experimental group and the control group,30 cases in each group.The experimental group was treated with sufentanil and propofol anesthesia and the control group was treated with fentanyl and propofol anesthesia.Patient vital signs,anesthesia time,recovery time and dosage of propofol between two groups were recorded and its nausea,vomiting,postoperative uterine pain and other adverse reactions were observed.Result：Two groups of patients in 5 min of MAP,HR,SpO2 and other indicators were significantly decreased compared with preoperative,the differences were statistically significant（P〈0.05）;but there was no statistical significance between the vital signs of two groups of patients（P〉0.05）.Anesthesia time and recovery time of the experimental group were shorter than the control group,and propofol of the experimental group was significantly reduced compared with the control group,the differences were statistically significant（P〈0.05）.Two groups of patients in the incidence of nausea and vomiting were no significant differences,but the number of cases of uterine pain of the experimental group was significantly less than the control group,the difference was statistically significant（P〈0.05）.Conclusion：Small doses of sufentanil and propofol for painless surgery increases the safety and efficacy of surgery.It is more worthy in clinical application.