特利加压素治疗肝肾综合征的临床疗效分析

目的：探讨肝肾综合征患者的临床表现及治疗方法。方法：将2010年1月-2012年6月入住本院的肝肾综合征患者38例随机分为治疗组和对照组，每组19例。两组除常规治疗外，治疗组使用特利加压素进行治疗，对照组使用多巴胺按照3-5μg/（kg·h）持续静脉泵治疗。通过1周时间的疗程，对比两组患者治疗前后尿量、尿素氮、血清肌酐变化情况。结果：两组患者尿量、尿素氮、血清肌酐水平均有明显改善，但治疗组在疗效上更为显著，与对照组比较差异有统计学意义（P〈0.05）。结论：特利加压素在临床上对肝肾综合征患者具有显著的成效，值得在临床上大力推广及应用。

The Analysis of the Clinical Curative of Trey Vasopressin in Treatment of hepatorenal Syndrome

Objective：To explore the clinical manifestations and treatment of patients with hepatorenal syndrome. Method：Thirty-eight patients with the hepatorenal syndrome in the hospital from January 2010 to June 2012 were randomly divided into the treatment group and the control group, each group contained 19 cases. In addition to conventional therapy,the treatment group with terlipressin treatment,the control group received dopamine in accordance with the 3~5μg/（kg＆#183;h）continuous intravenous infusion therapy. By 1 week of treatment,to compare the urine,blood urea nitrogen, serum creatinine changes between the two groups before and after treatment. Result：The urine output,blood urea nitrogen,serum creatinine levels were significantly improved in both of the groups,but the treatment group was more significant in efficacy,and the difference between the two groups were statistically significant after treatment（P〈0.05）. Conclusion：Terlipressin with significant results in clinical hepatorenal syndrome patients,it is worth vigorously promotion and application in clinical practice.